The echinocandin classes of antifungal agents are often considered to be a class of
antifungal which display predominately fungicidal activity against Candida species.
However, from the results of this study these agents are primarily fungistatic and in some
instances display little to no inhibitory activity (38, 39, 40, 41, 42). This is consistent with
the findings of Varga et al. (46) that reported a primarily fungistatic activity with
caspofungin against a small number of C. parapsilosis and C. orthopsilosis isolates using
the same methodology (46). Fungicidal activity was reported with caspofungin against C.
metapsilosis in the study by Varga et al. (46), but only at 16 and 32 times the MIC (46).
The echinocandin classes of antifungal agents are often considered to be a class ofantifungal which display predominately fungicidal activity against Candida species.However, from the results of this study these agents are primarily fungistatic and in someinstances display little to no inhibitory activity (38, 39, 40, 41, 42). This is consistent withthe findings of Varga et al. (46) that reported a primarily fungistatic activity withcaspofungin against a small number of C. parapsilosis and C. orthopsilosis isolates usingthe same methodology (46). Fungicidal activity was reported with caspofungin against C.metapsilosis in the study by Varga et al. (46), but only at 16 and 32 times the MIC (46).
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