The HS-SPME-GC-MS technique was coupled with the standard
additions technique for the quantification of NDMA, NDEA, NDBA
and NPIP in red wines from different types of grape, from different
countries and having undergone different aging processes. No
NDEA or NPIP signals were detected in any of the wine samples.
Also, there was no NDMA signal identified in the Chilean wine.
The virtues of the technique were confirmed by the LOQ and
LOD values obtained. The quantification technique for detecting
the presence of NAms in red wine developed in this work offers
various advantages over traditional methods given its simplicity,
low cost, precision and environmental friendliness. However, it
was necessary to carry out a factorial analysis of the HS-SPME
parameters given the presence of ethanol in the samples.