Congestive Symptoms Congestive symptoms, including
lower limb edema, dyspnea, pulmonary congestion, jugular venous
distention, and hepatomegaly, were recorded from BL
through the consecutive treatment periods. Lower limb edema
and pulmonary congestion were evaluated by symptomatic grading
(none, mild, moderate, and severe). Dyspnea, jugular venous
distention, and hepatomegaly were evaluated by their presence
or absence.