Déat-Lainé and co-workers (2013) reported high levels of
encapsulation by placing lyophilised WPI-alginate microparticles
in solutions of insulin. O’Neill et al. (2014) expanded on this
sorption approach by encapsulating a range of compounds in preformed
whey microbeads. This research showed that hydrophobic
interactions between the microbeads and the compounds to be
encapsulated could be used to increase the total percentage encapsulation.
In addition, it was shown that the entrapment of the
compounds within the microbeads was occurring via a process of
partition. Egan, O’Riordan, O’Sullivan, and Jacquier (2014) encapsulated
charged peptides in preformed whey protein microbeads
using a similar sorbent method. Adjusting the pH of peptide solutions
to facilitate an electrostatic interaction between the peptides
and the microbead resulted in high levels of peptide encapsulation.