A total of
297 mutation events in 296 cases (2.78% compared with 10636),
including 295 cases with one-locus and 1 case with two-locus
mismatch were found. Genotypes of parents and children, and
steps, origin and direction of 297 mutations at 33 loci are shown in
Table S1. The average mutation rate across all the 33 loci was
0.70
103, which was significantly lower than other reports
(p < 0.05) [16–18] even after excluding non-CODIS loci and/or loci
only reported in this study (Table S2 and Table S3). The observed
locus-specific mutation rates ranged from 0.20
103 (TPOX) to
1.96
103 (FGA), which was in the range reported by Qian et al