Refractory & recurrent ovarian cancer, metastatic breast cancer Monotherapy: 50 mg/m2 by IV infusion over 60 min every 4 wk. In combination: 30-40 mg/m2 IV every 4 wk. AIDS-related KS 20 mg/m2 by IV infusion over 60 min every 2-3 wk. Refractory & relapsed multiple myeloma 30 mg/m2 IV on day 4 in combination w/ bortezomib every 3 wk.