Down syndrome are low muscle tone, small stature, an upward slant to the eyes, and a single deep crease across the center of the palm - although each person with Down syndrome is a unique individual and may possess these characteristics to different degrees, or not at all. - See more at: http://www.ndss.org/Down-Syndrome/What-Is-Down-Syndrome/#sthash.2mUm9ALq.dpuf