A number of 3-alkoxy-1,2-dioxolanes exhibit promising levels of antimalarial activity against Plasmodium falciparum. A new route to the 1,2-dioxolane core is reported based on tandem peroxidation/cyclization of enones.
A number of 3-alkoxy-1,2-dioxolanes exhibit promising levels of antimalarialactivity against Plasmodium falciparum. A new route to the 1,2-dioxolane core is reportedbased on tandem peroxidation/cyclization of enones.