This study was designed to examine the effects of graded levels of dietary VA on survival, growth, blood biochemical and immune parameters, and resistance against infectious Aeromonas hydrophila challenge in Wuchang bream. We hypothesized that Wuchang bream fed with the optimum requirement of dietary VA will improve fish growth and immune ability and be more resistant to A. hydrophila challenge. These data will be important considerations in feed formulations for this species.