Materials and methods: This study was carried out on 57 male albino rats divided into nine groups.
Rats of experimental groups were exposed to cigarette smoke from a total of 100 cigarettes per week
for four weeks in a specially designed chamber. The antioxidants used (vitamin C, E, and B-carotene)
were administrated at low (9, 7.2, and 0.27 mg/day) and high doses (18, 14.4, and 0.54 mg/day),
respectively, through gastric feeding tubes. The lipid profile was estimated, and the carotids and heart
were removed, weighed, and then processed, and the carotid intima-media thickness was measured.
Statistical analysis was performed using the Statistical Package for Social Sciences