Highlights
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Platelet activating factor (PAF) associates with inflammatory cytokines in acute dengue.
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Monocyte derived macrophages produced inflammatory cytokines following infection with the DENV.
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Monocyte derived macrophages did not produce PAF following DENV infection alone.
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Antibody dependent enhancement did not induce production of PAF from monocytes.
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Lipopolysaccharide acts synergistically with the DENV to induce production of PAF.