The statistical analysis of depression score of the students coming from three academic streams demonstrate a significant difference, that is, the students coming from Humanities and Social Sciences were suffering from more depression followed by students from Management and Science background. Although the reasons are not clear at the moment, it is possible that it may be related to better job prospect for the students from Science and Management background in the Indian society. The issue requires attention of the academic administration of Humanities and Social Science departments of the university. Special classes should be organized for the Humanities and Social Science students to make them psychologically more competent to develop skills and adopt effective strategies to manage stress and symptoms of depression. Earlier studies where comparison was made between students enrolled in law and medical faculties, significant difference was found in the depression scores of students in the said two faculties (Gutierrez, 1985 and Dammeyer and Nunez, 1999). This is consistent with Khawaja and Duncanson (2008), who found higher level of depression among the university Faculties of Health, Law, and Education. Students from the Faculty of Health, for example, were found to have the lowest level of depression compared to the other Faculties (Khawaja and Duncanson, 2008).