In the present investigation, the overall results from the preliminary
phytochemical screening of the seed extracts (petroleum
ether, benzene, chloroform, acetone, methanol, ethanol
and methanol–ethyl acetate) of A. cocculus revealed the potentials
for developing antimicrobial pharmaceutical substances
from them. The basic forms of phytochemicals present in these
Table 3 Minimal inhibitory concentrations (MICs) of A. cocculus seed extracts.
A. cocculus extracts MIC (lg/mL)
S. aureus P. vulgaris E. coli S. typhi K. pneumoniae
Petroleum ether extract 9 11 11 11 9
Benzene extract 7 NT NT NT 9
Chloroform extract 13 13 11 NT 9
Acetone extract 5 7 7 7 7
Methanol extract 5 7 3 5 7
Ethanol extract 7 NT NT 7 11
Methanol–ethyl acetate extract 13 15 13 NT 13
NT=not tested as there was no activity.
102 U. Qadir et al.