Electrical stimulation. Research suggests that pulsed electrical stimulation might assist in the development of cartilage, and it has long been used as an adjunctive therapy to address pain and ultimately improve function. Hulme and colleagues
conducted a systematic review of three RCTs and controlled clinical trials that compared pulsed electromagnetic
fields or direct electrical stimulation with placebo in 259 patients with knee OA. Both forms of electrical stimulation were included in the review because they act by the same mechanism. The primary outcome examined was pain, and secondary
outcomes included physical function, joint imaging, patient global function, and stiffness, among others. The authors concluded that electrical stimulation therapy produced small to moderate statistically significant effects on all outcomes (SMD, −0.59 to –0.91), with clinical benefit ranging from 13% to 23% over placebo. With the exception of knee pain, these benefits did not meet the requirement for clinical significance as defined by Felson of a 20% improvement in four of six measures.28 The limited number of studies, the fact that the same research team conducted two of the three trials, and
the varied application of the modality limit the conclusions that can be made. Further research is warranted.
Electrical stimulation. Research suggests that pulsed electrical stimulation might assist in the development of cartilage, and it has long been used as an adjunctive therapy to address pain and ultimately improve function. Hulme and colleaguesconducted a systematic review of three RCTs and controlled clinical trials that compared pulsed electromagneticfields or direct electrical stimulation with placebo in 259 patients with knee OA. Both forms of electrical stimulation were included in the review because they act by the same mechanism. The primary outcome examined was pain, and secondaryoutcomes included physical function, joint imaging, patient global function, and stiffness, among others. The authors concluded that electrical stimulation therapy produced small to moderate statistically significant effects on all outcomes (SMD, −0.59 to –0.91), with clinical benefit ranging from 13% to 23% over placebo. With the exception of knee pain, these benefits did not meet the requirement for clinical significance as defined by Felson of a 20% improvement in four of six measures.28 The limited number of studies, the fact that the same research team conducted two of the three trials, andthe varied application of the modality limit the conclusions that can be made. Further research is warranted.
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