The liver tissue of common
carp revealed different degree of hydropic degeneration, vacuolisation, pyknotic nuclei, and fatty
infiltration. The gills of common carp displayed varied degrees of epithelial hypertrophy, telangiectasis,
oedema with epithelial separation from basement membranes, general necrosis, and epithelial desquamation.
After a 20-d recovery treatment, the antioxidant enzyme activities and MDA content were significantly
lower (p < 0.05) than in the corresponding exposure groups in all of the highest doses, but not in
the lower doses. To our knowledge, this is the first report of subchronic oxidative stress and histopathological
effects caused by ATR, CPF and their mixture in the common carp.