Processing & Efficacy
The ability for schizophyllan to produce a physiological response is directly correlated with the extraction process and subsequent processing the compound endures. This theory also coincides with that of other beta-glucans.
High dosage amounts of schizophyllan are not the primary determinant of an immunological response. Studies have validated that 10 mg (or less) of a high quality, adequately processed chemically similar beta-glucan is a sufficient dose to elicit a measurable effect on immune cells. In addition, small particle beta-glucans modified to prevent re-aggregation during digestion have the most positive effects on immune potentiation.[9]