The men stand accused of murdering David Miller, 24, and raping and murdering Hannah Witheridge, 23, on the Thai diving resort of Koh Tao on Sept 15.
Zaw Lin and Wai Phyo, both migrant workers aged 21, were formally indicted for trial on Thursday and are due to enter a plea on Monday, according to prosecutors on nearby Koh Samui, where the case will be heard.
"The court will ask the defendants whether they confess or deny the charges," chief prosecutor Paiboon Archavanuntakun told AFP.
The pair -- who did not appear in court on Thursday -- are also accused of battery and illegal entry to Thailand, among other charges, he added.
They were arrested in October after police said they had found the men's DNA on Witheridge's body and that they had admitted to