5. Effect of curcumin supplementation on exercise-induced
oxidative stress, inflammation, and muscle damage
Curcumin has beneficial effects on conditions such as injured
skeletal muscles. It has been shown that curcumin reduces
inflammatory cytokine concentration in skeletal muscles after
downhill running [32]. In addition, Kawanishi et al. observed that
curcumin attenuates oxidative stress following downhill-running–
induced muscle damage. They reported that hydrogen peroxide
concentration and NADPH-oxidase mRNA in downhill-running
mice were significantly higher than in the resting mice; however,
these variables were significantly attenuated by Theracurmin
administration in the downhill-running mice.