In another study comparing the cytotoxicity of magnetiteloaded polylactide (PLA) nanoparticles, polylactide/glycolide
(PLA/GA) nanoparticles and SLN using human granulocytes, the effective concentration to reduce the cell viability in the MTT test to 50%was 0.38% for high molecularweight PLA, 0.30% for lowmolecularweight PLA, 0.15% for PLA/GA and over 10% for SLN.