We looked at the relationship between coffee consumption and overall mortality in the Nurses’ Health Study and the Health Professionals Follow-Up Study, which together included about 130,000 study volunteers. (1) At the start of the study, these healthy men and women were in their 40s and 50s. We followed them for 18 to 24 years, to see who died during that period, and to track their diet and lifestyle habits, including coffee consumption. We did not find any relationship between coffee consumption and increased risk of death from any cause, death from cancer, or death from cardiovascular disease. Even people who drank up to six cups of coffee per day were at no higher risk of death. This finding fits into the research picture that has been emerging over the past few years. For the general population, the evidence suggests that coffee drinking doesn’t have any serious detrimental health effects.