In contrast to the antibacterial activity test using
the disc diffusion method, the MIC and MBC values
of citronella grass oil were in the range of 0.005–
0.3 and 0.6–1.2 ll/ml, respectively (see Table 2).
Citronella grass oil was the most effective essential
oil against P. acnes whereas the MBC value of
kaffir lime oil (5 ll/ml) indicated that this oil was
less effective than that of lemongrass oil (MBC
0.6 ll/ml) and citronella grass oil (MBC 0.6–
1.2 ll/ml). The essential oil of citronella grass had
the lowest MIC and MBC, whereas ginger oil had
the highest (75 ll/ml). The MBC values of holy basil
oil (5–10 ll/ml) and sweet basil oil (50 ll/ml) indicate
that P. acnes was more susceptible to holy basil
oil than to sweet basil oil. Except for citronella
oil, the MICs of the essential oils corresponded to
their MBCs, suggesting a bactericidal effect on P.
acnes.
The different antimicrobial activity of the essential
oils may be due to their different chemical compositions.
Pauli (2001) analyzed antimicrobial data
of substances mainly found in essential oils and
found that most monoterpenes do not possess a wide
spectrum of activity at low dose. Sesquiterpene
alcohols and fatty acids exhibit weak antimicrobial
properties towards Gram-negative bacteria. A small
number of substances in essential oils, the aldehyde
and phenolic compounds, are able to inhibit bacteria,
moulds, dermatophytes and yeasts at low concentrations.
In this study, the key constituents of
citronellal and geranial in citronella grass and kaffir
lime oils, citral in lemongrass oil, eugenol in holy basil
oil, linalool in sweet basil and terpinen-4-ol in plai
oil, may account for their efficacy (Abe et al., 2003;
Carson and Riley, 1995; Lee et al., 2005; Sacchetti
et al., 2005; Tawil and Yousef, 1988).
In contrast to the antibacterial activity test using
the disc diffusion method, the MIC and MBC values
of citronella grass oil were in the range of 0.005–
0.3 and 0.6–1.2 ll/ml, respectively (see Table 2).
Citronella grass oil was the most effective essential
oil against P. acnes whereas the MBC value of
kaffir lime oil (5 ll/ml) indicated that this oil was
less effective than that of lemongrass oil (MBC
0.6 ll/ml) and citronella grass oil (MBC 0.6–
1.2 ll/ml). The essential oil of citronella grass had
the lowest MIC and MBC, whereas ginger oil had
the highest (75 ll/ml). The MBC values of holy basil
oil (5–10 ll/ml) and sweet basil oil (50 ll/ml) indicate
that P. acnes was more susceptible to holy basil
oil than to sweet basil oil. Except for citronella
oil, the MICs of the essential oils corresponded to
their MBCs, suggesting a bactericidal effect on P.
acnes.
The different antimicrobial activity of the essential
oils may be due to their different chemical compositions.
Pauli (2001) analyzed antimicrobial data
of substances mainly found in essential oils and
found that most monoterpenes do not possess a wide
spectrum of activity at low dose. Sesquiterpene
alcohols and fatty acids exhibit weak antimicrobial
properties towards Gram-negative bacteria. A small
number of substances in essential oils, the aldehyde
and phenolic compounds, are able to inhibit bacteria,
moulds, dermatophytes and yeasts at low concentrations.
In this study, the key constituents of
citronellal and geranial in citronella grass and kaffir
lime oils, citral in lemongrass oil, eugenol in holy basil
oil, linalool in sweet basil and terpinen-4-ol in plai
oil, may account for their efficacy (Abe et al., 2003;
Carson and Riley, 1995; Lee et al., 2005; Sacchetti
et al., 2005; Tawil and Yousef, 1988).
การแปล กรุณารอสักครู่..
