Low-dose proton beam radiation had an obvious effect on the
MIA PaCa-2 cell line, a laboratory model for pancreatic
carcinoma. Viability data are in line with the data on apoptosis
and showed gradually increasing cell death in the irradiated
cultures up to 72 h after exposure. Recruitment of repair
proteins began immediately after radiation as demonstrated
by gH2AX mobilization; however, cell cycle arrest and,
therefore, the majority of repair processes started only at
24 h after irradiation.