After stroke, 25% to 75% of the patients reported of experiencing depression, which is one of the major predictors of total QOL [32]. We assessed depression using the BDI at an average of 3.59±4.06 weeks after stroke and found no significant difference between the patients with paralysis on dominant and non-dominant hands. Several meta-analyses have found no correlation between brain lesion location and depression [32,33]. Nelson et al. [34] reported that time was an important factor for depression. They compared depression in patients with left and right hemisphere lesions at 2 weeks, 2 months, and 6 months after stroke and found that although depression resolved in patients with right hemisphere lesions after 2 months, they experienced more recurrence at 6 months compared to the patients with left hemisphere lesions. Our finding is consistent with that of Nelson et al. [34], which indicates that there was no difference in occurrence of depression between the groups at the subacute stage of stroke.