concluded that some microbes secrete some extracellular enzymes such as chitinase, cellulase, glucanase and protease which digest the fungal mycelia. E. nidulans NK-62 produce cellulase and xylanase which hydrolyse the fungal wall ( Kango et al., 2003). Also, E. nidulans antagonized the growth of the pathogenic fungus F. oxysporum which causes wilt disease in tomato ( Sibounnavong et al., 2008).