Few trials have been conducted over longer periods. One of
those studies examined energy balance during the overfeeding of
liquid formula diets containing MCT (61% octanoate, 32% decanoate)
or LCT (32% oleate, 51% linoleate) for 7 d (7). EE was
measured on d 1 and 6 for 10–15 min every 30 min for 6 h after
meal consumption. The thermic effect of food (TEF) was identified
as 8% of ingested energy after MCT consumption compared
with 5.8% after LCT consumption on d 1. After 6 d, TEF was 12
and 6.6% of ingested energy with MCT and LCT consumption,
respectively, indicating that the difference in EE between MCT
and LCT persists even after a week of overfeeding.