The European project RISTOMED (www.ristomed.eu), a multicenter ‘open-label’ randomized study (CORDIS FP7), was designed to develop and provide a healthy, personalized and balanced dietary intervention, enriched or not with specific nutraceutical compounds, to decrease and prevent inflammageing, oxidative
stress and gut microbiota alteration in healthy elderly people. RISTOMED diet was built to reach the recommended daily requirement of nutrients, vitamins and minerals complying with different cultural patterns. RISTOMED diet was designed with a particular attention towards those foods and nutrients known or suspected to be able to reduce inflammation and oxidative stress by promoting a healthy gut microbiota in elderly people [12].