showed that synergism between radiotherapy and
anti-CTLA4 antibody therapy in poorly immunogenic tumors could be explained by radiation-induced upregulation of the NKGD2
tumor cells [125]. Therapeutic efficiency of radiotherapy and
ipilimumab in metastatic, castration-resistant prostate cancers was
receptor on effector T cells, which improved their interaction with
also investigated in several trials [126,127]. Son et al. studied the
efficiency of combining anti-CTLA4 blockade and radiotherapy with
dendritic cell therapy in murine colon cancer and found synergistic
effects