Results: A total of 274 critically ill patients requiring endotracheal intubation were included; 113 intubations using
ML and 117 intubations using the C-MAC® were assessed. In patients with at least one predictor for difficult
intubation, the C-MAC® resulted in more successful intubations on first attempt compared with ML (34/43, 79% vs.
21/38, 55%; P = 0.03). The visualization of the glottis with ML using Cormack and Lehane (C&L) grading was more
frequently rated as difficult (20%, C&L grade 3 and 4) compared with the C-MAC® (7%, C&L grade 3 and 4) (P <
0.0001).