Of the 5,229 neonatal admissions over the period, a total of 1,153 (22.1%) were admitted
for neonatal hyperbilirubinemia. Complete records for 1,118 infants were available for analysis.
The incidence of acute bilirubin encephalopathy (ABE) and exchange transfusion (ET)
were 17.0% (95% CI: 14.9%–19.3%) and 31.5% (95% CI: 28.8%–34.3%) respectively. A
total of 61 (5.5%, 95% CI: 4.3%–6.9%) of the jaundiced infants died. Weight on admission,
peak total serum bilirubin (TSB), sepsis and exposure to hemolytic products were predictive
of ABE, while age on admission, peak TSB, ABO incompatibility and ABE were predictive of
ET. Rhesus incompatibility, asphyxia, exposure to hemolytic substances and ABE were
associated with elevated mortality risk, while ET was a protective factor. Lack of routine irradiance
monitoring and steady energy supply were frequent challenges for conventional
blue-light phototherapy.
Of the 5,229 neonatal admissions over the period, a total of 1,153 (22.1%) were admittedfor neonatal hyperbilirubinemia. Complete records for 1,118 infants were available for analysis.The incidence of acute bilirubin encephalopathy (ABE) and exchange transfusion (ET)were 17.0% (95% CI: 14.9%–19.3%) and 31.5% (95% CI: 28.8%–34.3%) respectively. Atotal of 61 (5.5%, 95% CI: 4.3%–6.9%) of the jaundiced infants died. Weight on admission,peak total serum bilirubin (TSB), sepsis and exposure to hemolytic products were predictiveof ABE, while age on admission, peak TSB, ABO incompatibility and ABE were predictive ofET. Rhesus incompatibility, asphyxia, exposure to hemolytic substances and ABE wereassociated with elevated mortality risk, while ET was a protective factor. Lack of routine irradiancemonitoring and steady energy supply were frequent challenges for conventionalblue-light phototherapy.
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