Sweet ‘N Low (saccharin): The pink packets sitting on your table at the local diner contain only four calories and can be used in baking, as saccharin is heat-stable. Saccharin does not raise blood sugar levels, so this is another alternative that is preferable for individuals with diabetes. Unfortunately, many individuals who use this sweetener note a bitter aftertaste. A word of caution: The National Cancer Institute outlines research done in the 1970s that found probable links of saccharin with the development of bladder cancer, although in 2000 it was delisted from the U.S. National Toxicology Program’s Report on Carcinogens because there was no clear, definitive evidence directly linking saccharin to bladder cancer in humans.