Norhashimah et al. [6] proposed brain lesion segmentation in DWI images based on thresholding technique. In this research, brain lesion includes solid tumor, acute infarction, haemorrhage and abscess. DWI images were normalized, background was removed and the images were enhanced with two different techniques: Gamma-law transformation and contrast stretching. The results revealed that thresholding with gamma-law transformation provided better segmentation results than that with contrast stretching.