Search methods for identification of studies
Electronic searches
We searched CENTRAL (The Cochrane Library), MEDLINE,
EMBASE and CINAHL databases up to September 2005 (using
the search terms: (bleed or rebleed or haemorrhage or hemorrhage)
and any of the generic names of proton pump inhibitors), using
the Cochrane Upper Gastrointestinal and Pancreatic Diseases
(UGPD) model (Appendix 1).We also searched the National Research
Register (NRR) and the UGPD trials register. The search
strategy was then re-run in February 2006 and in October 2008.
The search provided a comprehensive list of primary studies, both
published and unpublished, that complied with the inclusion criteria.
Free-text searches and medical subject headings were combined
to identify papers concerned with PPIs and upper gastrointestinal
bleeding.