Among the pharmaceutical packaging, blisters represent the
largest segment of the market (Swain,1998), which give an efficient
protection to drugs in terms of moisture, light and oxygen barrier.
Pharmaceutical blisters consist chiefly of plastic films (80e85 wt%)
and aluminum foils (15e20 wt%) (Pilchik, 2000), and are processed
by thermoforming or coldforming method. Fig. 1 shows the major
components of blister packaging.