The presence of depressive symptomswas the only predictor
of fatigue intensity and interference among the potential
contributors to fatigue. Interestingly, in the univariate analysis,
women reported significantly greater fatigue intensity and interference
compared with men; however, after controlling
for depressive symptoms, there were no gender differences,
indicating that depressed mood was a dominant factor. Finally,
fatigue intensity and interference were correlated with
poor HRQoL. Patients with higher PHQ-9 scores (depressive
symptoms) reported more interference from fatigue and fatigue
intensity. On the basis of the regression analysis