Preeclampsia affects 5-10% of pregnancies and is a major cause of maternal and fetal morbidity and mortality in developing countries(1). The exact etiology of preeclampsia remains unknown, however, many studies have demonstrated that preeclampsia is associated with failure of trophoblastic invasion of the maternal spiral arteries, leading to increased vascular resistance of the uterine arteries and decreased uteroplacental blood flow(2). The ability to predict early, women who have risk of this disease would be of great values. Although there is no proven effective method for the prevention of the preeclampsia, routine antenatal care has the aim to identify women who are at risk for more intensive antenatal care.