A heavy responsibility is placed on macrophage cells as a shield against various infectious agents because of its phagocytotic, digestive and secretory functions. Through its secretions and receptors, macrophage
participates in complex interactions involving cellular and humoral components of the inflammatory
and immunologic networks [1]. Among the important products of macrophage is nitric oxide (NO) which is a diatomic free radical molecule that has various biological effects. It is produced from its precursor L-arginine by macrophage