Rare deaths have been described in patients infected with Zika virus (online Technical Appendix reference 44). Besides 1 infant death, 3 other fatalities were reported (2 from Brazil and 1 from Colombia): 1 man with lupus erythematosus, chronic corticosteroid use, rheumatoid arthritis, and alcoholism; and 2 girls 16 years of age, 1 with sickle cell disease (online Technical Appendix reference 59). (Medical history was not reported for the other girl [online Technical Appendix reference 44].)