As with most social problems, law enforcement alone will not get to the root of the drug-abuse issue. In spite of international conventions and regulatory agencies, national law and enforcement, and the cooperation of the International Criminal Police Organization (INTERPOL), illicit production, smuggling, drug addiction, and crime committed by sellers and users continue without significant letup. Synthetic drugs are easy to produce and difficult to regulate. The countries of Southeast Asia have been ineffective in controlling the production of opium. Turkey, with United States financial support, cut production by subsidizing poppy farmers to grow substitute crops. Fabulous wealth is accumulated by drug barons as a result of the cocaine trade originating in South American countries. At the users ' end of the chain, a larger number of addicts with no source of cheap or legal supply will continue to make illicit sales so profitable as to invite high risks in supplying the demand. Society continues to grope for the "best" answers to this dilemma. To the control of production, manufacture, trade, and distribution of drugs must be added education, research, and treatment and rehabilitation of addicts if any impact is to be made on drug-abuse problems.