Ripe fruits of good quality were purchased from local markets at Ado-Ekiti and Kano, the capital cities of Ekiti and Kano States in Nigeria. The juice was then extracted using the L’Equip MINI Pulp Eject juice extractor. The children were divided into two groups based on a previously established block randomization list. The children in the first group were given the routine oral drugs for children with SCA (folic acid, vitamin B complex and proguanil) alone while those in the other group were given lime juice in addition to these routine drugs