A diagnosis of the HIV can easily be missed or delayed because there are often no symptoms in the early stages, and the infected person may be unaware of an HIV infection. Embarrassment and not being honest with a health care provider about sexual activity can also delay a diagnosis. In addition, some symptoms of HIV infection, such as weight loss and flu-like symptoms, can be vague and mimic many other conditions. These include influenza. Diagnosis may also be missed or delayed because HIV may not be detectable with diagnostic testing in the first one to three months after infection.Because of these factors, it is important to have regular medical care throughout a lifetime in order to maximize the chances of early diagnosis and treatment of HIV infection....more about HIV/AIDS »After one year on therapy, she noticed that her arms, thighs and buttocks were becoming slim and her back and stomach were protruding (see picture).A diagnosis of lipodystrophy was made, and the patient's treatment was changed to AZT/3TC/NVP. She took this regimen for 2 years (2007). In 2008, she developed anaemia thought to be secondary to AZT. As a result her treatment was changed to TDF/3TC/EFV. . She took this regimen faithfully till May 2011. At this time she had her first CD4 cell count and HIV RNA tests.The CD4 cell count was as >800 cell/mL and the HIV RNA was <400 copies/mL. On personal initiative, the patient visited South Africa and underwent a thorough medical examination in May 2011 including HIV testing. The HIV test using rapid tests was negative and a confirmatory Western blot was also negative. HIV RNA was undetectable.She was informed of the results and advised to stop HIV treatment and return in 3 months for repeat tests. The repeat tests were unchanged. It was concluded that this lady was never HIV positive.
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