To our knowledge, this is thefirst randomized clinical trial
exploring the effects ofintensive andlong-term exercise on
the physicalfunctioning ofhome-dwelling patientswithAD
and their use of health and social services. The expected
deteriorationin these patients’ physicalfunctioningwas delayedwithhome-delivered,individuallytailoredexercisewithout
causing any harm or risks.Theinterventionwas administeredwithoutincreasing
the total health and social service
costs. Our study suggests that group exercise may even decrease
the use and costs of other health and social services.
There was a mean 7-point difference in the FIM ratings
between the HE group and the CG. Although this
did not reach the predetermined level, we believe this 6%
difference is clinically meaningful because it indicates less
need for help in several daily activity categories. Very few
prior clinical intervention trials have demonstrated beneficial
effects in the physical functioning of patients with
AD.9 Successful exercise interventions have usually positively
affected functional limitations, such as walking
speed, balance, and muscle strength,24-26 which may or
may not translate into improved functioning in everyday
life. Prior interventions successful in improving physi-