Biocatalytic processes are often limited by poor yields or productivities
and in situ product removal can be rather advantageous.
It can resolve the problem of product inhibition or thermodynamic
equilibrium [1], and enable selective removal of the product
from the biocatalyst. This can also provide benefits for the subsequent
downstream processing [2], and can minimize product losses
avoiding its degradation [1]. The coupling of reaction and in situ
product separation process has been becoming more important in
the industrial processes due to the necessity to make them more
efficient and less energy demanding [3].