4. Conclusion
In this study, a sensitive and selective method was successfully
developed for the assay of FEX in pharmaceutical preparations. The proposed method was based on sensitized terbium
time resolved luminescence. The enhancement of the terbium
luminescence upon complexation with FEX has enabled the
assay of this drug with high sensitivity and selectivity where
short-lived emissions were efficiently eliminated. The procedure was applied for the determination of FEX in various
tablets with excellent recoveries and reproducibility. The proposed method has the advantage of being simpler, more rapid,
and suitable for automation. It is sensitive to the low amount
of fexofenadine. As a result, the proposed method represents
excellent analytical alternative for the determination of