The objective of this workshop was to bring together through an open invitation members of the solvent development community, government agencies, environmental organizations, academic researchers, industry, and other stakeholders to discuss different approaches to evaluating toxicity of solvents for CO2 capture, particularly in face of proprietary issues. A “state of the science” review regarding the toxicity of amines, their degradation products, and their atmospheric and environmental transformation products was conducted through presentation of the participants’ recent research results and group discussion on several workshop charge questions. The charge questions were as follows: