An increase in the liver weight was observed in diabetic animals might be due to decreased breakdown of glycogen. It was reported in previous studies that 15% rise in kidney weight within 72 h of induction of STZ in experimental diabetic rats. This may be due to the glomerular cell proliferation accompanying glomerular enlargement in the early phase of STZ-induced diabetes in rats. Treatment with GG and RS were failed to reverse STZ induced change in the weight of liver and kidney to a significant extent.