In the present study, we showed for the first time that drinking
2 glasses of orange juice (500 mL) daily increases plasma vitamin C
concentrations by 40–64%. Interestingly, changes in vitamin C
were significantly inversely correlated with concentrations of
8-epi-PGF2, suggesting that vitamin C may play a critical role in
reducing the formation of compounds produced by the random
oxidation of phospholipids by oxygen radical