3. Results
3.1. Case 1
Two workers were admitted to hospital after collapsing in an enclosed waste intake area of an animal rendering plant. One was unconscious on admission. Both provided urine samples whilst at the hospital – worker 1 (male, 53 years old) approximately 9 h after the incident, worker 2 (male, 54 years old) at an unknown time (but apparently the same day) by catheter as he was still unconscious. The urine sample for worker 1 contained 326 μmol/l thiosulphate (23 mmol/mol creatinine), which is consistent with the levels seen in other survivors of reported incidents of hydrogen sulphide exposure where samples have been taken between 2 and 15 h of the incident (Kage et al., 1997 and Kage et al., 2002). Worker 2’s result (10 μmol/l, 2 mmol/mol creatinine) was within previously reported background levels (Kangas and Savolainen, 1987 and Chwatko and Bald, 2009) however it is not clear when the sample was collected in relation to the incident. It is possible that, if he was exposed, it might take a couple of hours for his thiosulphate level to exceed background levels (as demonstrated by a volunteer study (Kangas and Savolainen, 1987)); so if the sample was taken shortly after the incident, the sample may not reflect the extent of his exposure to hydrogen sulphide. Equally, if the sample had been taken later, the level of thiosulphate may already have reduced to background levels. There is previously reported, (Kage et al., 1997) a case (in which a man lost consciousness due to hydrogen sulphide exposure and subsequently recovered) where the urinary thiosulphate level was less than 3 μmol/l when the sample was taken 15 h after the incident.
There was evidence that worker 1 had been exposed to hydrogen sulphide in sufficient amounts to cause a feeling of unwellness or even unconsciousness. The sample of worker 2 did not demonstrate evidence of hydrogen sulphide exposure but this does not exclude the possibility of exposure due to the unknown timing of sample collection.
3. ผลลัพธ์3.1. กรณีที่ 1Two workers were admitted to hospital after collapsing in an enclosed waste intake area of an animal rendering plant. One was unconscious on admission. Both provided urine samples whilst at the hospital – worker 1 (male, 53 years old) approximately 9 h after the incident, worker 2 (male, 54 years old) at an unknown time (but apparently the same day) by catheter as he was still unconscious. The urine sample for worker 1 contained 326 μmol/l thiosulphate (23 mmol/mol creatinine), which is consistent with the levels seen in other survivors of reported incidents of hydrogen sulphide exposure where samples have been taken between 2 and 15 h of the incident (Kage et al., 1997 and Kage et al., 2002). Worker 2’s result (10 μmol/l, 2 mmol/mol creatinine) was within previously reported background levels (Kangas and Savolainen, 1987 and Chwatko and Bald, 2009) however it is not clear when the sample was collected in relation to the incident. It is possible that, if he was exposed, it might take a couple of hours for his thiosulphate level to exceed background levels (as demonstrated by a volunteer study (Kangas and Savolainen, 1987)); so if the sample was taken shortly after the incident, the sample may not reflect the extent of his exposure to hydrogen sulphide. Equally, if the sample had been taken later, the level of thiosulphate may already have reduced to background levels. There is previously reported, (Kage et al., 1997) a case (in which a man lost consciousness due to hydrogen sulphide exposure and subsequently recovered) where the urinary thiosulphate level was less than 3 μmol/l when the sample was taken 15 h after the incident.มีหลักฐานว่าผู้ปฏิบัติงาน 1 ได้รับการสัมผัสกับไฮโดรเจนซัลไฟด์ในปริมาณที่เพียงพอจะทำให้เกิดความรู้สึกของ unwellness หรือแม้กระทั่งสู่การหมดสติ ตัวอย่างของผู้ปฏิบัติงาน 2 ได้แสดงให้เห็นถึงหลักฐานของไฮโดรเจนซัลไฟด์ แต่ไม่ได้ยกเว้นเป็นไปได้ของแสงเนื่องจากไม่ทราบระยะเวลาการเก็บตัวอย่าง
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