Sick Building Syndrome (SBS) is the health disorders, eye, nose, throat, respiratory, and skin among workers in the office. Sick building is associated with the period of stay in the building. But you can’t determine the exact cause. This problem may be occurred only a portion of the building or everywhere you stay in the building. The symptoms are non-specific symptoms and often in office. These problems often occurred after had come in the building, which could be because of poor building design from the beginning, or maintenance of a building is not effective, but another reason is possible are activities occurring within the building, inadequate ventilation, chemical diffusing indoors in high volumes, chemicals from outside the building, and biological agents.