The concept of biocompatible, osteoconductive and noninflammatory material mimicking the structure of natural bone has
generated a considerable interest in recent decades. Hydroxyapatite (HA) is an important bionic material that is used for bone
grafting in osseous defects and drug carriers. HA with various morphologies and surface properties have been widely investi-
gated. In this paper, HA nanofibers are produced through a combination of electrospinning and sol-gel technique. The mor-
phologies, composition and structure are investigated by Scanning Electron Microscopy (SEM), Thermogravimetic Analysis
(TGA), Fourier Transform Infrared (FTIR), X-ray Diffraction (XRD) patterns, Transmission Electron Microscopy (TEM). The
results show that HA nanofibers are even and well-crystallized, and pH is crucial for producing HA nanofibers. With the change
of pH from 4 to 9, nanofibers grow densely along (210) plane and become compact while surface area, pore volume and pore
size decrease correspondingly. The synthesized HA nanofibers are nontoxic and safe. Zn can be also incorporated into HA
nanofibers, which will endow them with more perfect function.
The concept of biocompatible, osteoconductive and noninflammatory material mimicking the structure of natural bone hasgenerated a considerable interest in recent decades. Hydroxyapatite (HA) is an important bionic material that is used for bonegrafting in osseous defects and drug carriers. HA with various morphologies and surface properties have been widely investi-gated. In this paper, HA nanofibers are produced through a combination of electrospinning and sol-gel technique. The mor-phologies, composition and structure are investigated by Scanning Electron Microscopy (SEM), Thermogravimetic Analysis(TGA), Fourier Transform Infrared (FTIR), X-ray Diffraction (XRD) patterns, Transmission Electron Microscopy (TEM). Theresults show that HA nanofibers are even and well-crystallized, and pH is crucial for producing HA nanofibers. With the changeof pH from 4 to 9, nanofibers grow densely along (210) plane and become compact while surface area, pore volume and poresize decrease correspondingly. The synthesized HA nanofibers are nontoxic and safe. Zn can be also incorporated into HAnanofibers, which will endow them with more perfect function.
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