where this condition is relatively more common.[8] Hb electrophoresis was ordered which revealed Hb A of 14.8% (normal range: 94.3–98.5%), Hb E of 82.8% (normal range: 0.00%) and Hb F of 2.4% (normal range: 0–2%). HbA1C could not be detected as Hb A2, and HbA1C co-eluted at the same time and could not be separated. Hb E disease was diagnosed (homozygous state)